Cannabidiolic acid (CBDA) occurs in the resin glands (trichomes) of the cannabis plant. It is the precursor of cannabidiol (CBD). CBDA is considered inactive. Cannabidiolic acid | C22H30O4 | CID - structure, chemical names, ; UNII-FJX8O3OJCD; Cannabidiol Acid; FJX8O3OJCD; CBDA More. Cannabis is unique among flora due to its ability to produce cannabinoids like cannabidiolic acid (CBDA), as well as the more famous.
or Acid CBDA Cannabidiolic
This is usually accomplished through heat application, which can be done with either cooking or smoking the plant. This is why some raw plants, if juiced, will not have active THC in them since it has not been activated through heat.
It is also necessary to mention that your metabolic system alone will not necessarily decarboxylate things. For example, according to Aphios, a Delaware research company, the compound of THCA can be very unstable outside of a living organism.
The reason it is called decarboxylation is the chemical structure involved in CBDa. Cannabidiolic acid actually comes from yet another acid, cannabigerolic acid. According to a study found in the Journal of Biological Chemistry, the enzyme responsible for this transformation can be purified. It is called CBDa synthase.
It catalyzes the oxidative cyclization of cannabigerolic-acid into CBDa. We have known for a while that different strains of cannabis plants can be grown. What they found was rather astonishing. We are, on average, Medical Genomics was surprised, then, by their finding that cannabis strains can differ by a figure equivalent to 10 times the variation of the human genome.
When trying to figure out the concentration of cannabinoids in certain strains, bear in mind that, with the advent of dispensaries in America, producers are breeding new strains more than we breed dogs and cats.
Strains are frequently being invented for their varying effects, either for psychotropic means or for soothing therapeutic means. And, as mentioned in the previous paragraph, the genetic variety between these strains is actually relatively vast. Here is a list of some of the well-known, high-CBD strains: It was also the highest occurring cannabinoid found in industrial hemp fiber-based cannabis. And finally, hemp products are generally taken from the stalk, and not the flowers, of the cannabis sativa plant.
Just like all the other raw cannabinoids, CBDA is found in mature hemp or marijuana that is ready for harvest. Despite this compound being extremely abundant in the plants used to create the CBD-rich products on the market today, finding CBDA can be though.
This is because the vast majority of extractors decarboxylate, or heat, the extracted cannabinoids in order to activate them.
While you could simply eat cannabis to ingest this compound, most of the time that isn't a great option. Most companies creating a CBDA-rich product use a low-temperature juicing or extraction process to extract these raw compounds. As an example, hemp would be cold pressed much like a vegetable juice. A blended product containing raw and activated cannabinoids, as opposed to simply activated cannabinoids, has the potential to unlock an even higher level of the entourage effect.
This could explain why products containing 1: As a consumer looking for a CBDA rich product, we suggest looking for brands like Endoca that are focused on providing raw cannabinoid products. Your email address will not be published. Share Tweet Reddit Email. Anti-proliferative - prevents cancer cell migration, noted specifically in cases of aggressive breast cancer. Source Antiemetic - reduces nausea and vomiting.
Source Anti-inflammatory and pain reduction through COX-2 inhibition. Source Positive effect on seizures for the treatment of epilepsy, also when used in combination with CBD.
September 13, Last Updated:
What You Need to Know about Cannabidiolic Acid (CBDa)
Cannabidiolic acid (CBDA) was first isolated in the 50's. Then (like most other minor cannabinoids), not a whole lot happened with it for several. Effect of combined doses of Δ(9)-tetrahydrocannabinol (THC) and cannabidiolic acid (CBDA) on acute and anticipatory nausea using rat (Sprague- Dawley). Cannabidiolic Acid (CBDA) is the acid precursor to the famous phytocannabinoid CBD. Learn about this compound and explore its effects and.