MONDAY, May 7, (HealthDay News) -- Cannabidiol (CBD) oil has become the hot new product in states that have legalized medical marijuana. Dec 20, What are the benefits of CBD — and is it safe to use? A prescription cannabidiol (CBD) oil is considered an effective anti-seizure medication. Feb 26, CBD oil is made by extracting CBD from the cannabis plant, then diluting CBD oil has even been used to safely treat insomnia and anxiety in.
Safe? Is CBD Oil
This is because THC breaks down when we apply heat and introduce it into the body. Unlike THC, it is not psychoactive. This means that CBD does not change a person's state of mind when they use it. However, CBD does appear to produce significant changes in the body, and some research suggests that it has medical benefits. The least processed form of the cannabis plant is hemp. Hemp contains most of the CBD that people use medicinally.
Hemp and marijuana come from the same plant, Cannabis sativa , but the two are very different. Over the years, marijuana farmers have selectively bred their plants to contain high levels of THC and other compounds that interested them, often because the compounds produced a smell or had another effect on the plant's flowers.
However, hemp farmers have rarely modified the plant. These hemp plants are used to create CBD oil. The human body produces certain cannabinoids on its own. It also has two receptors for cannabinoids, called the CB1 receptors and CB2 receptors. The CB1 receptors in the brain deal with coordination and movement, pain, emotions, and mood, thinking, appetite, and memories, and other functions. THC attaches to these receptors.
CB2 receptors are more common in the immune system. They affect inflammation and pain. People tend to use prescription or over-the-counter drugs to relieve stiffness and pain, including chronic pain. Authors of a study published in the Journal of Experimental Medicine found that CBD significantly reduced chronic inflammation and pain in some mice and rats.
The researchers suggested that the non-psychoactive compounds in marijuana, such as CBD, could provide a new treatment for chronic pain. Some promising evidence suggests that CBD use may help people to quit smoking. A pilot study published in Addictive Behaviors found that smokers who used inhalers containing CBD smoked fewer cigarettes than usual and had no further cravings for nicotine.
A similar review, published in Neurotherapeutics found that CBD may be a promising treatment for people with opioid addiction disorders. The researchers noted that CBD reduced some symptoms associated with substance use disorders. These included anxiety , mood-related symptoms, pain, and insomnia.
More research is necessary, but these findings suggest that CBD may help to prevent or reduce withdrawal symptoms. After researching the safety and effectiveness of CBD oil for treating epilepsy, the FDA approved the use of CBD Epidiolex as a therapy for two rare conditions characterized by epileptic seizures in The types of seizures that characterize LGS or DS are difficult to control with other types of medication.
The FDA specified that doctors could not prescribe Epidiolex for children younger than 2 years. A physician or pharmacist will determine the right dosage based on body weight. Authors of a review noted that CBD has anti-seizure properties and a low risk of side effects for people with epilepsy.
Findings suggested that CBD may also treat many complications linked to epilepsy, such as neurodegeneration, neuronal injury, and psychiatric diseases. Another study, published in Current Pharmaceutical Design, found that CBD may produce effects similar to those of certain antipsychotic drugs, and that the compound may provide a safe and effective treatment for people with schizophrenia. However, further research is necessary. Some researchers have found that CBD may prove to combat cancer.
Authors of a review published in the British Journal of Clinical Pharmacology found evidence that CBD significantly helped to prevent the spread of cancer. The researchers also noted that the compound tends to suppress the growth of cancer cells and promote their destruction. They pointed out that CBD has low levels of toxicity. They called for further research into its potential as an accompaniment to standard cancer treatments. Doctors often advise people with chronic anxiety to avoid cannabis, as THC can trigger or amplify feelings of anxiousness and paranoia.
However, authors of a review from Neurotherapeutics found that CBD may help to reduce anxiety in people with certain related disorders. According to the review, CBD may reduce anxiety-related behaviors in people with conditions such as:.
The authors noted that current treatments for these disorders can lead to additional symptoms and side effects, which can cause some people to stop taking them. No further definitive evidence currently links CBD to adverse effects, and the authors called for further studies of the compound as a treatment for anxiety. Type 1 diabetes results from inflammation that occurs when the immune system attacks cells in the pancreas. Research published in by Clinical Hemorheology and Microcirculation found that CBD may ease this inflammation in the pancreas.
This may be the first step in finding a CBD-based treatment for type 1 diabetes. A paper presented in the same year in Lisbon, Portugal, suggested that CBD may reduce inflammation and protect against or delay the development of type 1 diabetes. Acne treatment is another promising use for CBD.
The condition is caused, in part, by inflammation and overworked sebaceous glands in the body. A study published by the Journal of Clinical Investigation found that CBD helps to lower the production of sebum that leads to acne, partly because of its anti-inflammatory effect on the body. Sebum is an oily substance, and overproduction can cause acne.
Initial research published in the Journal of Alzheimer's Disease found that CBD was able to prevent the development of social recognition deficit in participants. This means that CBD could help people in the early stages of Alzheimer's to keep the ability to recognize the faces of people that they know. This is the first evidence that CBD may slow the progression of Alzheimer's disease.
Cannabis is legal for either medicinal or recreational use in some American states. Other states have approved the use of CBD oil as a hemp product but not the general use of medical marijuana. Some state and federal laws differ, and current marijuana and CBD legislation in the U.
There is an ever-changing number of states that do not necessarily consider marijuana to be legal but have laws directly related to CBD oil. The following information is accurate as of May 8, , but the laws change frequently. However, state legislators generally approve the use of CBD oil at various concentrations to treat a range of epileptic conditions. A full list of states that have CBD-specific laws is available here. Different states also require different levels of prescription to possess and use CBD oil.
In Missouri, for example, a person can use CBD of a particular composition if they can show that three other treatment options have failed to treat their epilepsy. Anyone considering CBD oil should speak with a local healthcare provider. They can provide information about safe CBD sources and local laws surrounding usage. This is one of more than 80 active chemicals in marijuana. The new product was approved to treat seizures associated with two rare, severe forms of epilepsy in patients two years of age and older.
Many small-scale studies have looked into the safety of CBD in adults. They concluded that adults tend to tolerate a wide range of doses well. Researchers have found no significant side effects on the central nervous system , the vital signs, or mood, even among people who used high dosages. The most common side effect was tiredness. Also, some people reported diarrhea and changes in appetite or weight.
Concerning the product that the FDA approved to treat two types of epilepsy, researchers noticed following adverse effects in clinical trials:. The patient information leaflet notes that there is a risk of worsening depression or suicidal thoughts.
It is important to monitor anyone who is using this drug for signs of mood change. Research suggests that a person taking the product is unlikely to form a dependency. There is often a lack of evidence regarding the safety of new or alternative treatment options. Usually, researchers have not performed the full array of tests. Anyone who is considering using CBD should talk to a qualified healthcare practitioner beforehand.
When drugs do not have FDA approval, it can be difficult to know whether a product contains a safe or effective level of CBD. Unapproved products may not have the properties or contents stated on the packaging.
It is important to note that researchers have linked marijuana use during pregnancy to impairments in the fetal development of neurons. Regular use among teens is associated with issues concerning memory, behavior, and intelligence. CBD-based products come in many forms. Some can be mixed into different foods or drinks or taken with a pipette or dropper. Others are available in capsules or as a thick paste to be massaged into the skin. Some products are available as sprays to be administered under the tongue.
Recommended dosages vary between individuals, and depend on factors such as body weight, the concentration of the product, and the health issue. Due to the lack of FDA regulation for most CBD products, seek advice from a medical professional before determining the best dosage. As regulation in the U. After discussing dosages and risks with a doctor, and researching regional local laws, it is important to compare different brands of CBD oil.
There is a selection of CBD products available for purchase online. CBD was legalized in all 50 states by the Farm Bill, which served as the springboard for its explosive growth. However, this approval came with an important caveat. The legislation required extraction of CBD for academic research or under a state pilot program.
Since then, a number of states broadened this narrow definition, which legalized other CBD manufacturing processes. It is made by cold pressing the seeds on the cannabis plant. The resulting oil is high in inflammatory omega-6 fats. Hemp seeds contain no THC and hence the oil should technically not contain any either. Some countries require testing for THC in hemp seed oil to verify purity.
Typical requirements are that there are no more than or even zero parts per million ppm detected in the final product.
In comparison, hash or cannabis oil does contain high inducing THC. It is also misleadingly known as honey oil. It comes from aerial parts of the marijuana plant except the seeds.
Hash oil is illegal for recreational use in most states but is approved for medicinal use by a growing list of others. It is usually consumed by eating or smoking.
It is also sold in cartridges for use in vaping pens. In summary, while hemp seed oil is widely recognized as safe and available on healthfood store shelves all across the country, hemp oil is still regulated as as a medicinal only drug in some states and completely outlawed in others. CBD oil falls in the gray area somewhere between the two. The question that remains to be answered is its safety. Or is it actually more risky than consumers have been led to believe? The side effects of consuming cannabidiol are very real though commonly glossed over by those selling it.
CBD oil may potentially interact in a negative way with anti-epilepsy drugs. As of now, only in vitro test tube observations exist with no living organism testing proving safety.
Drugs that may interact include: While there is a well known link between psychotic disorders and pot, CBD is generally regarded as anti-psychotic. How can this be if a CBD side effect is psychosis? Perhaps cannabinoid oil purveyors tend to ignore the well established reactions because the side effect profile of CBD is better than pharmaceutical drugs used to treat similar conditions.
In addition, proponents of CBD oil use insist on its safety because cannabidiol is not mind altering like its cousin cannabinoid THC. Research from the s seems to confirm that CBD is well tolerated up to mg without psychotic episodes.
All three produced high inducing symptoms in mice. This research indicates that THC is not the only mind altering cannabinoid in hemp. It also suggests the possibility that a person can be exposed to brain altering, high inducing substances by simply consuming CBD. Researchers performed this conversion using artificial digestive juices.
The change accelerated in the presence of some kind of sugar or alcohol. In people consuming CBD oil, this would parallel as acidity in the stomach. Since people commonly consume CBD oil in sugary lattes, candy, goodies, smoothies or alcoholic beverages, this situation mimics the reality of many people who use it.
The researchers tested for the four most common symptoms of THC exposure including:. Follow-up research in published in the journal Cannabis and Cannabinoid Research gives additional pause. In their conclusion, researchers challenged the accepted premise that CBD is not high-inducing. The takeaway of existing research as of this writing seems to indicate extreme caution when it comes to ingestion of CBD oil especially by children.
Research definitively shows that THC exposure affects their developing brains in a negative way — perhaps permanently. The Journal of Current Pharmaceutical Design warns:. The literature not only suggests neurocognitive disadvantages to using marijuana in the domains of attention and memory that persist beyond abstinence, but suggest possible macrostructural brain alterations e.
The Journal Future Neurology warns that cannabis exposure crosses the placenta. Since CBD partially converts to THC under acidic conditions, women who consume CBD oil for morning sickness or other discomforts of pregnancy should understand that use may mimic using pot directly. Just because CBD oil is natural and works effectively to alleviate symptoms does not mean it is safe for your baby.
Some CBD products and oil come from plants other than cannabis. Hops is one that is popular currently. False marketing of these products encourages this line of thinking.
Everything you need to know about CBD oil
As more and more states legalize the use of marijuana, a product known as CBD oil has surged in popularity. A chemical compound found in the cannabis plant. Jul 27, After researching the safety and effectiveness of CBD oil for treating epilepsy, the FDA approved the use of CBD (Epidiolex) as a therapy for two. Sep 7, Consumer Reports shares details about safe CBD use. but not yet. and I can't use the CBD oil with THC that might work but if the V.A. finds a.